Effect of felodipine versus diuretics on left ventricular hypertrophy in orthotopic heart transplant recipients

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Regression of left ventricular hypertrophy in hypertensive heart transplant recipients treated with enalapril, furosemide, and verapamil.

BACKGROUND This prospective study was designed to examine whether left ventricular (LV) hypertrophy of the denervated transplanted heart may be reversed by medical therapy and, if so, to investigate the time course of this process and its effect on exercise capacity, myocardial function, and cardiac hemodynamics. METHODS AND RESULTS Ten hypertensive heart transplant recipients with LV hypertr...

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Orthotopic heart transplant versus left ventricular assist device: a national comparison of cost and survival.

OBJECTIVES Orthotopic heart transplantation is the standard of care for end-stage heart disease. Left ventricular assist device implantation offers an alternative treatment approach. Left ventricular assist device practice has changed dramatically since the 2008 Food and Drug Administration approval of the HeartMate II (Thoratec, Pleasanton, Calif), but at what societal cost? The present study ...

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Effect of Carvacrol on Catalase Activity and mRNA Expression Following Left Ventricular Hypertrophy in Rats

Background and Aims: Cardiac hypertrophy is a compensatory augmentation response of the heart due to pressure overload that can lead to heart failure. Carvacrol is considered as the major compound of many plants, that possesses strong antioxidant properties. The present study aimed to evaluate effect of carvacrol on catalase activity and mRNA expression following left ventricular hypertrop...

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Long-term Mortality in Adult Orthotopic Heart Transplant Recipients

Heart transplantation is now regarded as the treatment of choice for end-stage heart failure. To improve long-term results of the heart transplantation, we analyzed causes of death relative to time after transplantation. A total of 201 consecutive patients, 154 (76.6%) males, aged ≥ 17 yr underwent heart transplantation between November 1992 and December 2008. Mean ages of recipients and donors...

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Physiological versus pathological left ventricular hypertrophy

Athletes commonly develop what is regarded as a benign increase in cardiac mass in response to physical training. However, prolonged training may lead to a degree of cardiac remodeling that mimics hypertrophic cardiomyopathy (HCM). Left ventricular hypertrophy (LVH) can be defined echocardiographically as a left ventricular wall thickness (LVWT) of greater than 12mm. A LVWT of 12-16mm represent...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 1998

ISSN: 0735-1097

DOI: 10.1016/s0735-1097(98)81328-4